Name: Human GUCY2C/Guanylyl cyclase C Protein (GCC-HM201)
Brand: KactusBio
SKU: GCC-HM201-100UG
Price: 346.5 USD
Availability: InStock

ELISA binding curve of biotinylated anti-GUCY2C antibody to 0.1 µg/well human GUCY2C protein with hFc tag, measured by OD450 absorbance.

Human GUCY2C/Guanylyl cyclase C Protein (GCC-HM201)

Immobilized Human GUCY2C, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-GUCY2C Antibody, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC Test).

Human GUCY2C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human GUCY2C is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human GUCY2C, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-GUCY2C Antibody, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC Test).
Amino Acid Range: Ser24-Gln430

Catalog #GCC-HM201

Size

100UG

500UG

Order by 4pm ET for delivery on:

[{"id":42618358726878,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"GCC-HM201-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human GUCY2C\/Guanylyl cyclase C Protein (GCC-HM201) - 100UG","public_title":"100UG","options":["100UG"],"price":34650,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584220299486,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"GCC-HM201-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human GUCY2C\/Guanylyl cyclase C Protein (GCC-HM201) - 500UG","public_title":"500UG","options":["500UG"],"price":115500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Human GUCY2C/Guanylyl cyclase C Protein (GCC-HM201) Summary

Product Description	Recombinant Human GUCY2C/Guanylyl cyclase C Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser24-Gln430.
Product Background	Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets \| ADC targets

Human GUCY2C/Guanylyl cyclase C Protein (GCC-HM201) Specifications/Details

Protein	GUCY2C/Guanylyl cyclase C
Synonyms	Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Accession	P25092-1
Species	Human
Biotinylated	no
Amino Acid Range	Ser24-Gln430
Molecular Weight	The protein has a predicted MW of 72.8 kDa. Due to glycosylation, the protein migrates to 85-115 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human GUCY2C, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-GUCY2C Antibody, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC Test).
Product Tag	C-hFc (IgG1)
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human GUCY2C, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-GUCY2C Antibody, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC Test).
	Human GUCY2C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human GUCY2C is greater than 95% as determined by SEC-HPLC.