Name: Non-biotinylated Human GUCY2C/Guanylyl cyclase C Protein (GCC-HM401)
Brand: KactusBio
SKU: GCC-HM401-100UG
Price: 346.5 USD
Availability: InStock

Non-biotinylated Human GUCY2C/Guanylyl cyclase C Protein (GCC-HM401)

Immobilized Human GUCY2C, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GUCY2C Antibody, hFc Tag with the EC50 of 10.4ng/ml determined by ELISA.

Human GUCY2C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human GUCY2C is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human GUCY2C, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GUCY2C Antibody, hFc Tag with the EC50 of 10.4ng/ml determined by ELISA.
Amino Acid Range: Ser24-Gln430

Catalog #GCC-HM401

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Non-biotinylated Human GUCY2C/Guanylyl cyclase C Protein (GCC-HM401) Summary

Product Description	Recombinant human GUCY2C/Guanylyl cyclase C Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ser24-Gln430.
Product Background	Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets \| ADC targets

Non-biotinylated Human GUCY2C/Guanylyl cyclase C Protein (GCC-HM401) Specifications/Details

Protein	GUCY2C/Guanylyl cyclase C
Synonyms	Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Accession	P25092-1
Species	Human
Biotinylated	no
Amino Acid Range	Ser24-Gln430
Molecular Weight	The protein has a predicted MW of 48.8 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human GUCY2C, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GUCY2C Antibody, hFc Tag with the EC50 of 10.4ng/ml determined by ELISA.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human GUCY2C, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GUCY2C Antibody, hFc Tag with the EC50 of 10.4ng/ml determined by ELISA.
	Human GUCY2C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human GUCY2C is greater than 95% as determined by SEC-HPLC.