Human Her2/ErbB2 (S310F) Protein (HER-HM112)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Thr23-Thr652 (S310F)

Catalog: HER-HM112

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Product Description Recombinant Human Her2/ErbB2 (S310F) Protein is expressed from HEK293 with His tag at the C-terminus.It contains Thr23-Thr652 (S310F).

Product Background

ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane.

Product Category

Recombinant Protein

Target

Her2/ErbB2 (S310F)

Gene/Protein ID

P04626-1

Species

Human

Exact Sequence

Thr23-Thr652 (S310F)
Molecular Weight The protein has a predicted MW of 70.50 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Human Her2 (S310F) is greater than 95% as determined by SEC-HPLC.
Human Her2 (S310F) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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