Human IGFBP-7 Protein (IGF-HM2BP)
Human IGFBP-7 Protein (IGF-HM2BP)
Human IGFBP-7 Protein (IGF-HM2BP)
Human IGFBP-7 Protein (IGF-HM2BP)
  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human CD93, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IGFBP-7, hFc Tag with the EC50 of 0.69ug/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ser27-Leu282
Catalog #IGF-HM2BP
Regular price $203.00
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Product Description
Recombinant Human IGFBP-7 Protein Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ser27-Leu282.
Product Background
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
Product Category
Recombinant Protein
Target
IGFBP-7
Synonyms
IGFBP-7; IBP7; AGM; FSTL2; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Ser27-Leu282
Molecular Weight
The protein has a predicted MW of 27.5 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human CD93, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IGFBP-7, hFc Tag with the EC50 of 0.69ug/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
N-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human CD93, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IGFBP-7, hFc Tag with the EC50 of 0.69ug/ml determined by ELISA (QC Test).
Human IGFBP-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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