Name: Human Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-HM1AB)
Brand: KactusBio
SKU: ITG-HM1AB-100UG
Price: 412.5 USD
Availability: InStock

Human Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-HM1AB)

Human ITGA2&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human ITGA2&ITGB1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Tyr30-T1132(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail

Catalog #ITG-HM1AB

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Human Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-HM1AB) Summary

Product Description	Recombinant Human Integrin alpha 2 beta 1(ITGA2&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGA2.It contains Tyr30-T1132(ITGA2) acidic tail and Gln21-Asp728(ITGB1) basic tail.
Product Background	The α2β1 integrin, also known as VLA-2, GPIa-IIa, CD49b, was first identified as an extracellular matrix receptor for collagens and/or laminins. It is now recognized that the α2β1 integrin serves as a receptor for many matrix and nonmatrix molecules. It plays a critical role in platelet function and homeostasis.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-HM1AB) Specifications/Details

Protein	Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer
Synonyms	α2β1; Integrin alpha A1 beta 1; alpha A1 beta 1; alpha A1; beta 1; ITGA1&ITGB1; ITGA&ITGB; VLA-2, GPIa-IIa, CD49b;Integrin alpha A1 β 1; alpha A1 β 1; β 1
Accession	P17301-1(ITGA2)&P05556-1(ITGB1)
Species	Human
Biotinylated	no
Amino Acid Range	Tyr30-T1132(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail
Molecular Weight	The protein has a predicted MW of 126.6 kDa(ITGA2)&83.2 kDa(ITGB1). Due to glycosylation, the protein migrates to 110-140 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS, 8% trehalose (pH 7.4).
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Human ITGA2&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human ITGA2&ITGB1 is greater than 95% as determined by SEC-HPLC.