Name: Non-biotinylated Human LILRA3/CD85e Protein (LIL-HM4A3)
Brand: KactusBio
SKU: LIL-HM4A3-100UG
Price: 297.0 USD
Availability: InStock

Non-biotinylated Human LILRA3/CD85e Protein (LIL-HM4A3)

Human LILRA3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human LILRA is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gly24-Glu439

Catalog #LIL-HM4A3

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Non-biotinylated Human LILRA3/CD85e Protein (LIL-HM4A3) Summary

Product Description	Recombinant Human LILRA3/CD85e Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly24-Glu439.
Product Background	Human LILRA3, also known as Leukocyte Ig-like receptor 4 (LIR-4), CD85 antigen-like family member E, Immunogobulin-like transcript 6 (ILT-6) and monocyte inhibitory receptor HM43/HM31,- is a 70 kD Ig superfamily member that belongs to the leukocyte receptor complex/cluster. Mature LILRA3 is 416 amino acids (aa) in length and contains four C2-type Ig-like domains. Unlike other LILR family members, LILRA3 is actively secreted.LILRA3 acts as soluble receptor for class I MHC antigens. LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Non-biotinylated Human LILRA3/CD85e Protein (LIL-HM4A3) Specifications/Details

Protein	LILRA3/CD85e
Synonyms	CD85e; HM31; HM43; ILT6; ILT-6; LILRA3; LIR4; LIR-4HM43e3
Accession	Q8N6C8
Species	Human
Biotinylated	no
Amino Acid Range	Gly24-Glu439
Molecular Weight	The protein has a predicted MW of 47.9 kDa. Due to glycosylation, the protein migrates to 68-72 kDa based on Bis-Tris PAGE result.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Human LILRA3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human LILRA is greater than 95% as determined by SEC-HPLC.