Product Description |
Recombinant Human LIV-1/SLC39A6 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Phe29-Trp325. |
Product Background |
Zinc transporter ZIP6 (SLC39A6) or LIV-1 is a protein that belongs to a subfamily of proteins group that displays structural specifications of zinc transporters in the cell membrane. Overexpression of this protein is observed in breast, prostate, and kidney tumor cells. Lately, LIV-1 is a dependable marker for detection of estrogen receptor positive breast cancer, which can be used to detect luminal breast cancer type A. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
LIV-1/SLC39A6 |
Synonyms |
ZIP-6; LIV-1; SLC39A6; LIV1; ZIP6 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Phe29-Trp325 |
Molecular Weight |
The protein has a predicted MW of 60.39 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 69.5ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-hFc |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 69.5ng/ml determined by ELISA (QC Test). |
|
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Human LIV-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Human LIV-1 is greater than 95% as determined by SEC-HPLC. |
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