Human LIV-1/SLC39A6 Protein (LIV-HM201)
Human LIV-1/SLC39A6 Protein (LIV-HM201)
  • Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 69.5ng/ml determined by ELISA (QC Test).
  • Amino Acid Range: Phe29-Trp325
Catalog #LIV-HM201
Regular price $412.50
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Human LIV-1/SLC39A6 Protein (LIV-HM201) Summary

Product Description

Recombinant Human LIV-1/SLC39A6 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Phe29-Trp325.

Product Background

Zinc transporter ZIP6 (SLC39A6) or LIV-1 is a protein that belongs to a subfamily of proteins group that displays structural specifications of zinc transporters in the cell membrane. Overexpression of this protein is observed in breast, prostate, and kidney tumor cells. Lately, LIV-1 is a dependable marker for detection of estrogen receptor positive breast cancer, which can be used to detect luminal breast cancer type A.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human LIV-1/SLC39A6 Protein (LIV-HM201) Specifications/Details

Protein
LIV-1/SLC39A6
Synonyms
ZIP-6; LIV-1; SLC39A6; LIV1; ZIP6
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Phe29-Trp325
Molecular Weight
The protein has a predicted MW of 60.39 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 69.5ng/ml determined by ELISA (QC Test).
Product Tag
C-hFc (IgG1)

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 69.5ng/ml determined by ELISA (QC Test). Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 69.5ng/ml determined by ELISA (QC Test).
Human LIV-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human LIV-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human LIV-1 is greater than 95% as determined by SEC-HPLC. The purity of Human LIV-1 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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