Human LIV-1/SLC39A6 Protein (LIV-HM201)

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 46.7ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Phe29-Trp325

Catalog: LIV-HM201

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Product Description	Recombinant Human LIV-1/SLC39A6 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Phe29-Trp325.
Product Background	Zinc transporter ZIP6 (SLC39A6) or LIV-1 is a protein that belongs to a subfamily of proteins group that displays structural specifications of zinc transporters in the cell membrane. Overexpression of this protein is observed in breast, prostate, and kidney tumor cells. Lately, LIV-1 is a dependable marker for detection of estrogen receptor positive breast cancer, which can be used to detect luminal breast cancer type A.
Product Category	Recombinant Protein

Target	LIV-1/SLC39A6
Accession	Q13433-1
Species	Human
Amino Acid Range	Phe29-Trp325
Molecular Weight	The protein has a predicted MW of 60.39 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 46.7ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 46.7ng/ml determined by ELISA.
	The purity of Human LIV-1 is greater than 95% as determined by SEC-HPLC.
	Human LIV-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.