Human LIV-1/SLC39A6 Protein (LIV-HM201)

Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 98.4ng/ml determined by ELISA (QC Test).

Human LIV-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human LIV-1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 98.4ng/ml determined by ELISA (QC Test).
Amino Acid Range: Phe29-Trp325

Catalog #LIV-HM201

Price

$412⁵⁰

Size

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Human LIV-1/SLC39A6 Protein (LIV-HM201) Summary

Product Description

Recombinant Human LIV-1/SLC39A6 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Phe29-Trp325.

Product Background

Zinc transporter ZIP6 (SLC39A6) or LIV-1 is a protein that belongs to a subfamily of proteins group that displays structural specifications of zinc transporters in the cell membrane. Overexpression of this protein is observed in breast, prostate, and kidney tumor cells. Lately, LIV-1 is a dependable marker for detection of estrogen receptor positive breast cancer, which can be used to detect luminal breast cancer type A.

Human LIV-1/SLC39A6 Protein (LIV-HM201) Specifications/Details

Protein	LIV-1/SLC39A6
Synonyms	ZIP-6; LIV-1; SLC39A6; LIV1; ZIP6
Accession	Q13433-1
Species	Human
Biotinylated	no
Amino Acid Range	Phe29-Trp325
Molecular Weight	The protein has a predicted MW of 60.39 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 98.4ng/ml determined by ELISA (QC Test).
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human LIV-1, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 98.4ng/ml determined by ELISA (QC Test).
	Human LIV-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human LIV-1 is greater than 95% as determined by SEC-HPLC.