• Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Human MRGPRX2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-MRGPRX2 Antibody, mFc Tag with the EC50 of 11.1ng/ml determined by ELISA. The affinity constant of 0.16 nM as determined in SPR assay (Biacore T200).
  • Amino Acid Range: Met1-Val330
Catalog #MR2-HM1N118
Price
Regular price $1,44400
Regular price Sale price $1,44400
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Size
Avantor VWR Fisher Scientific

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Human MRGPRX2 Nanodisc (MR2-HM1N118) Summary

Product Description

 Recombinant Human MRGPRX2 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val330.

Product Background

 As receptor for multiple drugs, MRGPRX2 is crucial to drug-induced hypersensitivity. However, not only drugs, but also endogenous mediators like neuropeptides and host defense peptides activate MRGPRX2, suggesting its broad impact in cutaneous pathophysiology.

Human MRGPRX2 Nanodisc (MR2-HM1N118) Specifications/Details

Protein
 MRGPRX2
Synonyms
 MRGX2
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Met1-Val330
Molecular Weight
 The protein has a predicted MW of 39 kDa.
Activity
 Immobilized Human MRGPRX2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-MRGPRX2 Antibody, mFc Tag with the EC50 of 11.1ng/ml determined by ELISA. The affinity constant of 0.16 nM as determined in SPR assay (Biacore T200).
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage
 Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human MRGPRX2 Nanodisc, His Tag captured on CM5 Chip via Anti-His Antibody can bind Anti-MRGPRX2 Antibody, mFc Tag with an affinity constant of 0.16 nM as determined in SPR assay (Biacore T200). Human MRGPRX2 Nanodisc, His Tag captured on CM5 Chip via Anti-His Antibody can bind Anti-MRGPRX2 Antibody, mFc Tag with an affinity constant of 0.16 nM as determined in SPR assay (Biacore T200).
Immobilized Human MRGPRX2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-MRGPRX2 Antibody, mFc Tag with the EC50 of 11.1ng/ml determined by ELISA. Immobilized Human MRGPRX2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-MRGPRX2 Antibody, mFc Tag with the EC50 of 11.1ng/ml determined by ELISA.
Other Available Proteins:
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