Human MSLN/Mesothelin Protein (MSL-HM20D)
Catalog: MSL-HM20D
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| Product Description | Recombinant Human MSLN/Mesothelin Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala488-Ser600. |
Product Background |
Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally. |
Product Category |
Recombinant Protein |
Target |
MSLN/Mesothelin |
Gene/Protein ID |
Q13421-1 |
Species |
Human |
Exact Sequence |
Ala488-Ser600 |
| Molecular Weight | The protein has a predicted MW of 39.30 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Liquid |
| Shipping | Shipped with dry ice. |
| Formulation | Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
| Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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The purity of Human MSLN is greater than 95% as determined by SEC-HPLC. |
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Human MSLN on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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