Name: Human MSLN/Mesothelin Protein (MSL-HM20D)
Brand: KactusBio
SKU: MSL-HM20D-100UG
Price: 379.5 USD
Availability: InStock

Human MSLN/Mesothelin Protein (MSL-HM20D)

Immobilized Human MSLN, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-MSLN Antibody, hFc Tag with the EC50 of 15.5ng/ml determined by ELISA.

Human MSLN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human MSLN is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human MSLN, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-MSLN Antibody, hFc Tag with the EC50 of 15.5ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ala488-Ser600

Catalog #MSL-HM20D

Size

100UG

500UG

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Product Description	Recombinant Human MSLN/Mesothelin Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala488-Ser600.
Product Background	Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Protein	MSLN/Mesothelin
Synonyms	MSLN; CAK1; Mesothelin; MPF; MPFSMRP; SMR
Accession	Q13421-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala488-Ser600
Molecular Weight	The protein has a predicted MW of 39.30 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human MSLN, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-MSLN Antibody, hFc Tag with the EC50 of 15.5ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human MSLN, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-MSLN Antibody, hFc Tag with the EC50 of 15.5ng/ml determined by ELISA.
	Human MSLN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human MSLN is greater than 95% as determined by SEC-HPLC.