Product Description |
Recombinant Human PTK7/CCK4 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala31-Thr704. |
Product Background |
Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling. |
Product Category |
Recombinant Protein |
Target |
PTK7/CCK4 |
Synonyms |
CCK-4; PTK7 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala31-Thr704 |
Molecular Weight |
The protein has a predicted MW of 100.56 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human PTK7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human PTK7 is greater than 95% as determined by SEC-HPLC. |
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