Product Description |
Recombinant Human ROR1 Protein is expressed from Baculovirus-Insect Cells with His tag at the C-terminus.It contains Met453-Asn783. |
Product Background |
ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1),- is a member of- the ROR family within receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members. |
Product Category |
Recombinant Protein |
Target |
ROR1 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met453-Asn783 |
Molecular Weight |
The protein has a predicted MW of 39.21 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result. |
Activity |
The affinity constant of 26.40 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
C-His |
Express System |
Baculovirus-Insect Cells |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 20mM Tris, 500mM NaCl, 2mM GSH, 3mM DTT, 10% glycerol (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Anti-ROR1 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Human ROR1, His Tag with an affinity constant of 26.40 nM as determined in SPR assay (Biacore T200). |
|
|
Human ROR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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