Product Description |
Recombinant Human ROR2/NTRKR2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Val34-Gly403. |
Product Background |
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain. |
Product Category |
Recombinant Protein |
Target |
ROR2/NTRKR2 |
Synonyms |
BDB; BDB1; NTRKR2; ROR2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Val34-Gly403 |
Molecular Weight |
The protein has a predicted MW of 68 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human ROR2, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-ROR2 Antibody, hFc Tag with the EC50 of 20.9ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Immobilized Human ROR2, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-ROR2 Antibody, hFc Tag with the EC50 of 20.9ng/ml determined by ELISA. |
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|
Human ROR2 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. |
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The purity of- Human ROR2 is greater than 95% as determined by SEC-HPLC. |
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