Human HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein (MHC-HM430)

  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M)and AYACNTSTL peptide

Catalog: MHC-HM430

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Product Description Recombinant Human Survivin 2B(HLA-A*24:02) Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M) and AYACNTSTL peptide.

Product Background

Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.

Product Category

Recombinant Protein

Target

HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer
MHC Form Monomer
Allele HLA-A*24:02

Gene/Protein ID

AAA59600.1(HLA-A*24:02)&P61769(B2M)&AYACNTSTL

Species

Human

Exact Sequence

Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M)and AYACNTSTL peptide
Molecular Weight The protein has a predicted MW of 50.20 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.

Product Tag

C-His-Avi

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer is greater than 95% as determined by SEC-HPLC.
Human HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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