Name: Human Syndecan-1 Protein (SYN-HM201)
Brand: KactusBio
SKU: SYN-HM201-100UG
Price: 297.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human Syndecan-1, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Syndecan-1 Antibody, hFc Tag with the EC50 of 28.8ng/ml determined by ELISA.
Amino Acid Range: Gln23-Gly254

Catalog #SYN-HM201

Size

100UG

500UG

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Human Syndecan-1 Protein (SYN-HM201) Summary

Product Description	Recombinant Human Syndecan-1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gln23-Gly254.
Product Background	Syndecan-1 (SDC-1) is a heparan sulfate (HS)/chondroitin sulfate proteoglycan (PG) of the cell surface and the extracellular matrix (ECM), which regulates a broad spectrum of physiological and pathological processes such as cell proliferation, migration, inflammation, matrix remodeling, wound healing, and tumorigenesis. Syndecan-1 represents the major PG of the liver, expressed by hepatocytes and cholangiocytes, and its elevated expression is a characteristic feature of liver diseases.
Product Category	Recombinant Protein / Antibody discovery / ADC targets

Human Syndecan-1 Protein (SYN-HM201) Specifications/Details

Protein	Syndecan-1
Synonyms	Syndecan-1; SYND1; CD138; SDC1; SDC; SDC1
Accession	AAH08765
Species	Human
Biotinylated	no
Amino Acid Range	Gln23-Gly254
Molecular Weight	The protein has a predicted MW of 50.6 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Syndecan-1, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Syndecan-1 Antibody, hFc Tag with the EC50 of 28.8ng/ml determined by ELISA.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Syndecan-1, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Syndecan-1 Antibody, hFc Tag with the EC50 of 28.8ng/ml determined by ELISA.
	Human Syndecan-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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