Product Description |
Recombinant Mouse CADM1/IGSF4A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln48-Asp388. |
Product Background |
The cell adhesion molecule 1 (CADM1) is a molecule of cell adhesion with multiple functions and has been identified as a tumor suppressor gene. CADM1 has multifunctions on the pathogenesis of malignancies, and other normal cells such as immune cells. On the contrary to these cutaneous solid tumors except for Merkel cell carcinoma, cutaneous lymphomas, such as adult-T cell leukemia/lymphoma, mycosis fungoides, and Sézary syndrome, increase their CADM1 expression for the development of tumor environment. |
Product Category |
Recombinant Protein |
Target |
CADM1/IGSF4A |
Synonyms |
IgSF4; NECL-2; SgIgSF; SynCAM; TSLC-1; Cadm1; BL2; IGSF4; IGSF4A; RA175; ST17; TSLC1; sTSLC-1; sgIGSF; synCAM1; BL2; NECL2 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Gln48-Asp388 |
Molecular Weight |
The protein has a predicted MW of 39.1 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse CADM1/IGSF4A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse CADM1/IGSF4A is greater than 95% as determined by SEC-HPLC. |
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