Mouse CD160 Protein (CD1-MM260) Summary
Product Description |
Recombinant Mouse CD160 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly28-Ser160. |
Product Background |
CD160 (also Natural killer cell receptor BY55) is a 27 ‑ 30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic cells. CD160 antigenis a receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells. |
Product Category |
Recombinant Protein / Antibody discovery / Immune checkpoint proteins |
Mouse CD160 Protein (CD1-MM260) Specifications/Details
Protein |
CD160 |
Synonyms |
CD160;-BY55; BY55FLJ46513; NK1; NK28 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Gly28-Ser160 |
Molecular Weight |
The protein has a predicted MW of 41.8 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Mouse CD160 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Mouse CD160 is greater than 95% as determined by SEC-HPLC. |
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