Product Description |
Recombinant Mouse CD21 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile12-Trp963. |
Product Background |
A natural soluble form of CD21 that is cleaved from lymphocyte membrane CD21 circulates in normal human serum. Soluble CD21 retains the capacity to bind iC3b and CD23, the known ligands of membrane CD21. In a similar fashion to IgE complexes, another ligand of CD23, the soluble CD21 was shown to efficiently trigger CD23-signalling pathways in human monocytes. |
Product Category |
Recombinant Protein |
Target |
CD21 |
Synonyms |
EBV receptor; CD21; C3DR; CR2; C3DRSLEB9; CVID7; SLEB9 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Ile12-Trp963 |
Molecular Weight |
The protein has a predicted MW of 106.03 kDa. Due to glycosylation, the protein migrates to 130-160 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 90% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse CD21 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. |
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