Mouse CLEC4A/DCIR Protein (CLE-MM24A)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Gln70-Leu238

Catalog: CLE-MM24A

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Product Description Recombinant Mouse CLEC4A/DCIR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln70-Leu238.

Product Background

Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy.

Product Category

Recombinant Protein

Target

CLEC4A/DCIR
Synonyms CD367; Clec4a2; CLECSF6; DCIR; DDB27; HDCGC13P; LLIR; CLEC4A; DCIRLLIR

Gene/Protein ID

Q9QZ15

Species

Mouse

Exact Sequence

Gln70-Leu238
Molecular Weight The protein has a predicted MW of 46.3 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Tris-Bis PAGE result.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse CLEC4A/DCIR is greater than 95% as determined by SEC-HPLC.
Mouse CLEC4A/DCIR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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