Mouse IL-20RA Protein (IL2-MM2RA)
Mouse IL-20RA Protein (IL2-MM2RA)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: The affinity constant of 13.93 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Val33-Lys253
Catalog #IL2-MM2RA
Regular price $315.00
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Product Description
Recombinant Mouse IL-20RA Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Val33-Lys253.
Product Background
IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferation and immune evasion in CRC.Super-enhancer inhibition by JQ-1 or iBET-151 suppressed the growth of tumor cells and inhibited the expression of IL-20RA.
Product Category
Recombinant Protein
Target
IL-20RA
Synonyms
IL-20R-alpha; IL-20RA; CRF2-8; IL-20R1; ZcytoR7; FLJ40993
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Val33-Lys253
Molecular Weight
The protein has a predicted MW of 52.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Bis-Tris PAGE result.
Activity
The affinity constant of 13.93 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag
C-hFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse IL-20RA, hFc Tag captured on CM5 Chip via Protein A can bind Human IL-20, His Tag with an affinity constant of 13.93 uM as determined in SPR assay (Biacore T200).
Mouse IL-20RA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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