Mouse IL-20RA Protein (IL2-MM2RA)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Activity: The affinity constant of 13.93 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Val33-Lys253

Catalog: IL2-MM2RA

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Product Description Recombinant Mouse IL-20RA Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Val33-Lys253.

Product Background

IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferation and immune evasion in CRC.Super-enhancer inhibition by JQ-1 or iBET-151 suppressed the growth of tumor cells and inhibited the expression of IL-20RA.

Product Category

Recombinant Protein

Target

IL-20RA
Synonyms IL-20R-alpha; IL-20RA; CRF2-8; IL-20R1; ZcytoR7; FLJ40993
Accession

Species

Mouse

Amino Acid Range

Val33-Lys253
Molecular Weight The protein has a predicted MW of 52.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.

Activity

The affinity constant of 13.93 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse IL-20RA, hFc Tag captured on CM5 Chip via Protein A can bind Human IL-20, His Tag with an affinity constant of 13.93 uM as determined in SPR assay (Biacore T200).
Mouse IL-20RA on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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