Mouse Siglec-2/CD22 Protein (SIG-MM122)
Mouse Siglec-2/CD22 Protein (SIG-MM122)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser22–Arg702
Catalog #SIG-MM122
Regular price $297.00
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Product Description

Recombinant Mouse Siglec-2/CD22 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser22–Arg702.

Product Background

CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.

Product Category

Recombinant Protein / Antibody discovery / CAR-T targets

Protein

Siglec-2/CD22

Synonyms

CD22 molecule; CD22; Siglec-2; B-cell receptor CD22; BL-CAM; SIGLEC2; SIGLEC2FLJ22814

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Ser22–Arg702

Molecular Weight

The protein has a predicted MW of 80.25 kDa. Due to glycosylation, the protein migrates to 110-115 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse Siglec-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse Siglec-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse Siglec-2 is greater than 95% as determined by SEC-HPLC. The purity of Mouse Siglec-2 is greater than 95% as determined by SEC-HPLC.

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