Mouse TPBG/5T4 Protein (5T4-MM101)
Catalog: 5T4-MM101
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| Product Description | Recombinant Mouse TPBG/5T4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser32-Ser361. |
Product Background |
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs. |
Product Category |
Recombinant Protein |
Target |
TPBG/5T4 |
Gene/Protein ID |
Q9Z0L0 |
Species |
Mouse |
Exact Sequence |
Ser32-Ser361 |
| Molecular Weight | The protein has a predicted MW of 36.86 kDa. Due to glycosylation, the protein migrates to 52-70 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse TPBG is greater than 95% as determined by SEC-HPLC. |
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Mouse TPBG on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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