Rat CD40/TNFRSF5 Protein (CD4-RM140)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Val24-Arg193

Catalog: CD4-RM140

$240.00
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Product Description Recombinant Rat CD40/TNFRSF5 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Val24-Arg193.

Product Background

CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.

Product Category

Recombinant Protein

Target

CD40/TNFRSF5

Gene/Protein ID

A6JXD6

Species

Rat

Exact Sequence

Val24-Arg193
Molecular Weight The protein has a predicted MW of 20.39 kDa. Due to glycosylation, the protein migrates to 28-38 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Rat CD40 is greater than 95% as determined by SEC-HPLC.
Rat CD40 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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