Human PTK7/CCK4 Protein (CCK-HM104)
Human PTK7/CCK4 Protein (CCK-HM104)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ala31-Thr704
Catalog #CCK-HM104
Regular price $315.00
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Product Description
Recombinant Human PTK7/CCK4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala31-Thr704.
Product Background
Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling.
Product Category
Recombinant Protein
Target
PTK7/CCK4
Synonyms
CCK-4; PTK7
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Ala31-Thr704
Molecular Weight
The protein has a predicted MW of 75.7 kDa. Due to glycosylation, the protein migrates to 80-115 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human PTK7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human PTK7 is greater than 95% as determined by SEC-HPLC.

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