Product Description |
Recombinant Mouse LRRC15/LIB Protein is expressed from HEK293 with His tag at the C-Terminus.; It contains Tyr22-Gly536. |
Product Background |
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation.- LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. |
Product Category |
Recombinant Protein |
Target |
LRRC15/LIB |
Synonyms |
LIB; LRRC15 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Tyr22-Gly536 |
Molecular Weight |
The protein has a predicted MW of 58.56 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Anti-LRRC15 Antibody, hFc Tag at 2ug/ml (100 ul/well) on the plate. Dose response curve for Mouse LRRC15, His Tag with the EC50 of 9.6ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Immobilized Anti-LRRC15 Antibody, hFc Tag at 2ug/ml (100 ul/well) on the plate. Dose response curve for Mouse LRRC15, His Tag with the EC50 of 9.6ng/ml determined by ELISA (QC Test). |
|
|
Mouse LRRC15 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Mouse LRRC15 is greater than 95% as determined by SEC-HPLC. |
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