Human FGFR2 beta (IIIc) Protein (FGR-HM1BC)
Human FGFR2 beta (IIIc) Protein (FGR-HM1BC)
Human FGFR2 beta (IIIc) Protein (FGR-HM1BC)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human FGF basic, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human FGFR2 beta (IIIc), His Tag with the EC50 of 1.18ug/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Arg152-Glu377
Catalog #FGR-HM1BC
Regular price $379.50
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Product Description

Recombinant Human FGFR2 beta (IIIc) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg152-Glu377.

Product Background

Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha- isoform, or only IgII and IgIII, referred to as the beta- isoform.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Protein

FGFR2 beta (IIIc)

Synonyms

Fibroblast growth factor receptor 2;FGFR-2;KGFR;K-sam;Keratinocyte growth factor receptor;CD332;BEK;KSAM

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Arg152-Glu377

Molecular Weight

The protein has a predicted MW of 26.4 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human FGF basic, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human FGFR2 beta (IIIc), His Tag with the EC50 of 1.18ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human FGF basic, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human FGFR2 beta (IIIc), His Tag with the EC50 of 1.18ug/ml determined by ELISA. Immobilized Human FGF basic, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human FGFR2 beta (IIIc), His Tag with the EC50 of 1.18ug/ml determined by ELISA.
Human FGFR2 beta (IIIc) on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. Human FGFR2 beta (IIIc) on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
The purity of Human FGFR2 beta (IIIc) is greater than 95% as determined by SEC-HPLC. The purity of Human FGFR2 beta (IIIc) is greater than 95% as determined by SEC-HPLC.

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