Human ADAM9 Protein (ADM-HM109)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 1.0ng/ml determined by ELISA. See testing image for detail.Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2. The specific activity is > 25 pmol/min/ug.
Amino Acid Range: Ala206-Asp697

Catalog #ADM-HM109

Price

$330⁰⁰

Size

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Human ADAM9 Protein (ADM-HM109) Summary

Product Description	Recombinant Human ADAM9 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala206-Asp697.
Product Background	A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS.

Protein	ADAM9
Synonyms	ADAM 9; Meltrin-gamma; Mdc9; Mltng; Adam9; Kiaa0021; AU020942; MDC9; mKIAA0021; CORD9; MCMP; MLTNG
Accession	Q13443-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala206-Asp697
Molecular Weight	The protein has a predicted MW of 54.39 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 1.0ng/ml determined by ELISA. See testing image for detail.Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2. The specific activity is > 25 pmol/min/ug.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 20mM NaAc, 150mM NaCl, 0.01% Brij-35, 8% trehalose (pH 5.0).
Reconstitution	Dissolve the lyophilized protein in 20mM NaAc (pH 5.0). It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 1.0ng/ml determined by ELISA.
	Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Izeltabart, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA.
	Human ADAM9 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.