Mouse ACE2 Protein (ACE-MM102)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Gln18-Thr740

Catalog: ACE-MM102

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Product Description Recombinant Mouse ACE2 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln18-Thr740.

Product Background

 ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7.

Product Category

 Recombinant Protein

Target

 ACE2

Gene/Protein ID

 Q8R0I0-1

Species

 Mouse

Exact Sequence

 Gln18-Thr740
Molecular Weight The protein has a predicted MW of 84.57 kDa. Due to glycosylation, the protein migrates to 85-105 kDa based on Tris-Bis PAGE result.

Product Tag

 C-His

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH. The specific activity is >200 pmol/min/µg, as measured under the described conditions.
The purity of Mouse ACE2 is greater than 95% as determined by SEC-HPLC.
Mouse ACE2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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