APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM40GTC)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G&B2M&Peptide (RIIPRHLQL) Antibody, hFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide
Catalog #HLG-HM40GTC
Regular price $1,150.00
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Product Description

Recombinant APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly25-Thr305 (HLA-G), Ile21-Met119 (B2M) and RIIPRHLQL peptide.

Product Background

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.

Product Category

Recombinant Protein / Antibody discovery / MHC

Protein

HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer

Synonyms

HLA G antigen; sHLA-G; b2 microglobulin; HLA G; HLAG; HLA-G; MHC Class I Antigen G; MHC class Ib antigen; MHC-G; sHLA-G

MHC Form

Tetramer

Allele

HLA-G

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide

Molecular Weight

The protein has a predicted MW of 301.2 kDa.

Activity

Immobilized APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G&B2M&Peptide (RIIPRHLQL) Antibody, hFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Fluorophore

APC

Expression System

HEK293

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G&B2M&Peptide (RIIPRHLQL) Antibody, hFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test). Immobilized APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G&B2M&Peptide (RIIPRHLQL) Antibody, hFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test).
Serial dilutions of Anti-LILRB2 Antibody were added into APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag: Human LILRB2, mFc Tag binding reactioins. The half maximal inhibitiory concentration (IC50) is 62.7 ng/ml. Serial dilutions of Anti-LILRB2 Antibody were added into APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag: Human LILRB2, mFc Tag binding reactioins. The half maximal inhibitiory concentration (IC50) is 62.7 ng/ml.

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support@kactusbio.us

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