Biotinylated Human CD40 Ligand/TNFSF5 Trimer Protein (CDL-HM440B)

  • Express System: HEK293
  • Product Tag: N-His-Avi,N-Flag
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Biotinylated: yes
  • Exact Sequence: Met113-Leu261

Catalog: CDL-HM440B

$525.00
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Product Description Recombinant Biotinylated Human CD40 Ligand/TNFSF5 Trimer Protein is expressed from HEK293 with His tag, Avi tag and Flag tag at the N-terminus.It contains Met113-Leu261.

Product Background

CD40 ligand or CD40L, also called CD154,- is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.

Product Category

Recombinant Protein

Target

CD40 Ligand/TNFSF5 Trimer

Gene/Protein ID

P29965

Species

Human

Exact Sequence

Met113-Leu261
Molecular Weight The protein has a predicted MW of 54.51 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.

Product Tag

N-His-Avi,N-Flag

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Biotinylated Human CD40 Ligand Trimer is greater than 95% as determined by SEC-HPLC.
Biotinylated Human CD40 Ligand Trimer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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