Name: Biotinylated Human DR3/TNFRSF25 Protein (DR3-HM401B)
Brand: KactusBio
SKU: DR3-HM401B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human DR3/TNFRSF25 Protein (DR3-HM401B)

Immobilized Biotinylated Human DR3, His-Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human TNFSF15, hFc Tag with the EC50 of 15.2ng/ml determined by ELISA (QC Test).

Biotinylated Human DR3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Biotinylated Human DR3, His-Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human TNFSF15, hFc Tag with the EC50 of 15.2ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Gln25-Gln199

Catalog #DR3-HM401B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human DR3/TNFRSF25 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gln25-Gln199.
Product Background	Death Receptor 3 (DR3), also known as TNFRSF25, TRAMP, LARD, or WSL-1, is a death-domain-containing TNF-family receptor that, like its closest paralog TNFR1, binds the adaptor molecule TRADD through its cytoplasmic death domain. TRADD recruitment endows DR3 with dual-signaling capability to activate NF−κB and MAP-kinase signaling or alternatively trigger caspase activation and programmed cell death.
Product Category	Recombinant Protein / Antibody discovery

Protein	DR3/TNFRSF25
Synonyms	APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; TNFRSF25; LARD; TR3; TRAMP; WSL-LR
Accession	AAI17190.1
Species	Human
Biotinylated	yes
Amino Acid Range	Gln25-Gln199
Molecular Weight	The protein has a predicted MW of 26.40 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Biotinylated Human DR3, His-Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human TNFSF15, hFc Tag with the EC50 of 15.2ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human DR3, His-Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human TNFSF15, hFc Tag with the EC50 of 15.2ng/ml determined by ELISA (QC Test).
	Biotinylated Human DR3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.