Biotinylated Human IFN alpha/beta R1 Protein (IFN-HM4R1B)
Biotinylated Human IFN alpha/beta R1 Protein (IFN-HM4R1B)
Biotinylated Human IFN alpha/beta R1 Protein (IFN-HM4R1B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Anti-IFNAR1 Antibody, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IFNAR1, His Tag with the EC50 of 2.1ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Lys28-Lys436
Catalog #IFN-HM4R1B
Regular price $525.00
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Product Description
Recombinant Biotinylated Human IFN alpha/beta R1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Lys28-Lys436.
Product Background
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves.
Product Category
Recombinant Protein
Target
IFN alpha/beta R1
Synonyms
AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Lys28-Lys436
Molecular Weight
The protein has a predicted MW of 50.2 kDa. Due to glycosylation, the protein migrates to 75-100 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Anti-IFNAR1 Antibody, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IFNAR1, His Tag with the EC50 of 2.1ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
C-His-Avi
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Anti-IFNAR1 Antibody, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IFNAR1, His Tag with the EC50 of 2.1ng/ml determined by ELISA (QC Test).
Biotinylated Human IFNAR1 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
The purity of-Biotinylated Human IFNAR1 is greater than 95% as determined by SEC-HPLC.

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