Product Description |
Recombinant Biotinylated Human Mature TGF beta 3 Protein is expressed from HEK293 with Avi tag at the C-Terminus.It contains Ala301-Ser412. |
Product Background |
Transforming growth factor-beta 3 is a cytokine which is involved in cell growth regulation and differentiation, stimulation of extracellular matrix and modulation of immune responses. TGF beta 3 RNA is expressed in a diverse array of tissues including perichondrium, bone, intervertebral discs, mesenteries, pleura, heart, lung, palate, and amnion, as well as in central nervous system (CNS) structures such as the meninges, choroid plexus and the olfactory bulbs. Furthermore, in several organ systems, TGF beta 3 transcripts are expressed during periods of active morphogenesis suggesting that the protein may be an important factor for the growth and differentiation of many embryonic tissues. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
Mature TGF beta 3 |
Synonyms |
TGF-beta-3; LAP; TGFB3; ARVD; ARVD1; RNHF;TGF-β-3; TGF-beta 3 |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Ala301-Ser412 |
Molecular Weight |
The protein has a predicted MW of 14.53 kDa. Due to glycosylation, the protein migrates to 15-20 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human TGF-beta RII, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Mature TGF beta 3, Avi Tag with the EC50 of 23.5ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-Avi |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in 4mM HCl. Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in 4mM HCL. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Immobilized Human TGF-beta RII, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Mature TGF beta 3, Avi Tag with the EC50 of 23.5ng/ml determined by ELISA (QC Test). |
|
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Biotinylated Human Mature TGF beta 3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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