Name: Biotinylated Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-MM4V3B)
Brand: KactusBio
SKU: ITG-MM4V3B-100UG
Price: 525.0 USD
Availability: InStock

Biotinylated Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-MM4V3B)

Immobilized Human Vitronectin, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse ITGAV&ITGB3, His Tag with the EC50 of 3.2ug/ml determined by ELISA.

Biotinylated Mouse ITGAV&ITGB3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human Vitronectin, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse ITGAV&ITGB3, His Tag with the EC50 of 3.2ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail

Catalog #ITG-MM4V3B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail.
Product Background	ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.
Product Category	Recombinant Protein / Antibody discovery

Protein	Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer
Synonyms	αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3;Integrin alpha V β 3; β3
Accession	P43406(ITGAV)&O54890(ITGB3)
Species	Mouse
Biotinylated	yes
Amino Acid Range	Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail
Molecular Weight	The protein has a predicted MW of 108.77 kDa (ITGAV) & 80.84 kDa (ITGB3). Due to glycosylation, the protein migrates to 90-130 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Vitronectin, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse ITGAV&ITGB3, His Tag with the EC50 of 3.2ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Vitronectin, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse ITGAV&ITGB3, His Tag with the EC50 of 3.2ug/ml determined by ELISA.
	Biotinylated Mouse ITGAV&ITGB3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.