Product Description |
Recombinant Cynomolgus GAS6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala31-Ala637. |
Product Background |
Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM). |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
GAS6 |
Synonyms |
GAS-6; AXLLG; GAS6; DKFZp666G247; FLJ34709 |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Ala31-Ala637 |
Molecular Weight |
The protein has a predicted MW of 68.55 kDa. Due to glycosylation, the protein migrates to 69-74 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Cynomolgus GAS6, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-Gas6 Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA (QC Test). The affinity constant of 1.70 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Cynomolgus Axl, His Tag immobilized on CM5 Chip can bind Cynomolgus GAS6, His Tag with an affinity constant of 1.70 nM as determined in SPR assay (Biacore T200). |
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Immobilized Cynomolgus GAS6, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-Gas6 Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA (QC Test). |
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Cynomolgus GAS6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Cynomolgus GAS6 is greater than 95% as determined by SEC-HPLC. |
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