Name: Non-biotinylated Cynomolgus IL-17A/CTLA-8 Protein (ILA-CM417)
Brand: KactusBio
SKU: ILA-CM417-100UG
Price: 346.5 USD
Availability: InStock

Non-biotinylated Cynomolgus IL-17A/CTLA-8 Protein (ILA-CM417)

Immobilized Cynomolgus IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag with the EC50 of 0.10ug/ml determined by ELISA.

Immobilized Cynomolgus IL-17A, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-17A Antibody, hFc Tag with the EC50 of 4.4ng/ml determined by ELISA.

Cynomolgus IL-17A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Cynomolgus IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag with the EC50 of 0.10ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gly24-Ala155

Catalog #ILA-CM417

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus IL-17A/CTLA-8 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly24-Ala155.
Product Background	Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	IL-17A/CTLA-8
Synonyms	CTLA-8; IL17; IL17A; IL-17CTLA-8; interleukin 17A
Accession	XP_005552816.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gly24-Ala155
Molecular Weight	The protein has a predicted MW of 18.2 kDa. Due to glycosylation, the protein migrates to 26-32 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag with the EC50 of 0.10ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag with the EC50 of 0.10ug/ml determined by ELISA.
	Immobilized Cynomolgus IL-17A, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-17A Antibody, hFc Tag with the EC50 of 4.4ng/ml determined by ELISA.
	Cynomolgus IL-17A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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