Name: Cynomolgus IL-22R alpha 1 Protein (ILR-CM122)
Brand: KactusBio
SKU: ILR-CM122-100UG
Price: 346.5 USD
Availability: InStock

Cynomolgus IL-22R alpha 1 Protein (ILR-CM122)

Cynomolgus IL-22R alpha 1, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-22, His Tag with an affinity constant of 60.21 nM as determined in SPR assay (Biacore T200).

Cynomolgus IL-22R alpha 1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus IL-22R alpha 1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 60.21 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Pro18-Thr225

Catalog #ILR-CM122

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus IL-22R alpha 1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro18-Thr225.
Product Background	IL-22 receptor, also known as IL-22 R alpha 1 and CRF2-9, is an approximately 65 kDa transmembrane glycoprotein in the type II cytokine receptor family (CRF).Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	IL-22R alpha 1
Synonyms	IL-22R-alpha-1; IL-22RA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11
Accession	A0A2K5TKX9
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Pro18-Thr225
Molecular Weight	The protein has a predicted MW of 24.84 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 60.21 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus IL-22R alpha 1, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-22, His Tag with an affinity constant of 60.21 nM as determined in SPR assay (Biacore T200).
	Cynomolgus IL-22R alpha 1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus IL-22R alpha 1 is greater than 95% as determined by SEC-HPLC.

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