Product Description |
Recombinant Cynomolgus PADI4 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Pro663. |
Product Background |
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
PADI4 |
Synonyms |
Protein-arginine deiminase type-4; HL-60 PAD; HL60 PAD; HL-60; PAD; PAD4; PADI5; PDI5 |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Met1-Pro663 |
Molecular Weight |
The protein has a predicted MW of 76.6 kDa same as Bis-Tris PAGE result. |
Product Tag |
N-His |
Expression System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in 20mM Tris, 500mM Nacl,10% Glycerol, 0.5mM TCEP, 1mM EDTA (pH 8.0). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Cynomolgus PADI4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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