Cynomolgus PD-1/PDCD1 Protein (PD1-CM101)
Cynomolgus PD-1/PDCD1 Protein (PD1-CM101)
Cynomolgus PD-1/PDCD1 Protein (PD1-CM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus PD-1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus PD-L1, hFc Tag with the EC50 of 0.33ug/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Pro21-Gln167
Catalog #PD1-CM101
Regular price $379.50
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Product Description

Recombinant Cynomolgus PD-1/PDCD1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro21-Gln167.

Product Background

Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.

Product Category

Recombinant Protein / Antibody discovery / Immune checkpoint proteins
Protein
PD-1/PDCD1
Synonyms
PDCD1; PD1; CD279; SLEB2; PD-1
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Pro21-Gln167
Molecular Weight
The protein has a predicted MW of 17.53 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus PD-1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus PD-L1, hFc Tag with the EC50 of 0.33ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus PD-1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus PD-L1, hFc Tag with the EC50 of 0.33ug/ml determined by ELISA. Immobilized Cynomolgus PD-1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus PD-L1, hFc Tag with the EC50 of 0.33ug/ml determined by ELISA.
Immobilized Cynomolgus PD-1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PD-1 Antibody, hFc Tag with the EC50 of 4.1ng/ml determined by ELISA. Immobilized Cynomolgus PD-1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PD-1 Antibody, hFc Tag with the EC50 of 4.1ng/ml determined by ELISA.
Cynomolgus PD-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus PD-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus PD-1 is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus PD-1 is greater than 95% as determined by SEC-HPLC.
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