Product Description |
Recombinant Human Claudin 1 Protein-Nanodisc is expressed from HEK293 with His tag at the N-terminus (FITC-equivalent protein is fused on cytoplasmic part).It contains Met1-Val211. |
Product Background |
Claudin-1 (CLDN1), a major component of tight junction complexes in the epithelium, maintains cellular polarity, and plays a critical role in cell-to-cell communication as well as epithelial cell homeostasis. Moreover, CLDN1 expression is up-regulated in several cancers, and the level of CLDN1 expression has been proposed as a prognostic marker of patient survival. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc |
Protein |
Claudin 1 |
Synonyms |
Claudin-1; CLDN1; CLD1; SEMP1 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Val211 |
Molecular Weight |
The protein has a predicted MW of 48.5 kDa. |
Activity |
Immobilized Human Claudin 1 Nanodisc, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Claudin 1 Antibody, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
N-His |
Expression System |
HEK293 |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Immobilized Human Claudin 1 Nanodisc, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Claudin 1 Antibody, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA (QC Test). |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
More from Antibody Drug Discovery Proteins
Recently viewed
