Name: Human DR6/TNFRSF21 Protein (DR6-HM101)
Brand: KactusBio
SKU: DR6-HM101-100UG
Price: 165.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human DR6, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DR6 Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Gln42-His349

Catalog #DR6-HM101

Size

100UG

500UG

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Product Description	Recombinant Human DR6/TNFRSF21 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln42-His349.
Product Background	beta-amyloid precursor protein (APP) and death receptor 6 (DR6, also known as TNFRSF21) activate a widespread caspase-dependent self-destruction program. DR6 is broadly expressed by developing neurons, and is required for normal cell body death and axonal pruning both in vivo and after trophic-factor deprivation in vitro.DR6 is activated locally by an inactive surface ligand(s) that is released in an active form after trophic-factor deprivation.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	DR6/TNFRSF21
Synonyms	Death receptor 6; CD358; TNFRSF21; DR6; BM-018; MGC31965
Accession	O75509
Species	Human
Biotinylated	no
Amino Acid Range	Gln42-His349
Molecular Weight	The protein has a predicted MW of 34.3 kDa. Due to glycosylation, the protein migrates to 65-80 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human DR6, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DR6 Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human DR6, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DR6 Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA (QC Test).
	Human DR6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.