Name: Human Her3/ErbB3 Protein (HER-HM403)
Brand: KactusBio
SKU: HER-HM403-100UG
Price: 198.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His-Avi
Purity: >95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
Activity: Immobilized Human Her3, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 14.2ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Ser20-Thr643

Catalog #HER-HM403

Size

100UG

500UG

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Product Description	Recombinant Human Her3/ErbB3 is expressed from HEK293 with His tag and Avi tag at the C-Terminus; It contains Ser20-Thr643.
Product Background	Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Protein	Her3/ErbB3
Synonyms	ErbB3; ErbB-3; HER3; HER3c-erbB-3; LCCS2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; ERBB3
Accession	P21860-1
Species	Human
Biotinylated	no
Amino Acid Range	Ser20-Thr643
Molecular Weight	The protein has a predicted MW of 71.6 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Her3, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 14.2ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Her3, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 14.2ng/ml determined by ELISA (QC Test).
	Immobilized Human Her3, His Tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for Anti-Her3 Antibody, hFc Tag with the EC50 of 5.7 ng/ml determined by ELISA.
	Human Her3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Her3 is greater than 95% as determined by SEC-HPLC.