Product Description |
Recombinant Human Histone H2A type 3 Protein is expressed from E.coli without tag.It contains Ser2-Lys130. |
Product Background |
The family of histone H2A proved that there are a lot of variants associated with cancer development. HIST3H2A is a promising biomarker for predicting prognosis of pancreatic cancer, and it could be a potential therapeutic target. HIST3H2A might regulate the progression of tumor immune in pancreatic cancer through modulating the JAK-STAT pathway. In addition, the role HIST3H2A in pancreatic cancer may be related to DCST1-AS1, HIST1H2B, SLC12A9-AS1. |
Product Category |
Recombinant Protein |
Target |
Histone H2A type 3 |
Synonyms |
H2AC25; H2AW; HIST3H2A |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ser2-Lys130 |
Molecular Weight |
The protein has a predicted MW of 13.99 kDa. The protein migrates to 15-20 kDa based on Bis-Tris PAGE result. |
Product Tag |
No Tag |
Express System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human Histone H2A type 3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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