Human Histone H2A type 3 Protein (HIS-HE02A)

  • Express System: E.coli
  • Product Tag: No Tag
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Amino Acid Range: Ser2-Lys130

Catalog: HIS-HE02A

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Product Description Recombinant Human Histone H2A type 3 Protein is expressed from E.coli without tag.It contains Ser2-Lys130.

Product Background

The family of histone H2A proved that there are a lot of variants associated with cancer development. HIST3H2A is a promising biomarker for predicting prognosis of pancreatic cancer, and it could be a potential therapeutic target. HIST3H2A might regulate the progression of tumor immune in pancreatic cancer through modulating the JAK-STAT pathway. In addition, the role HIST3H2A in pancreatic cancer may be related to DCST1-AS1, HIST1H2B, SLC12A9-AS1.

Product Category

Recombinant Protein

Target

Histone H2A type 3
Accession

Species

Human

Amino Acid Range

Ser2-Lys130
Molecular Weight The protein has a predicted MW of 13.99 kDa. The protein migrates to 15-20 kDa based on Tris-Bis PAGE result.

Product Tag

No Tag

Express System

E.coli
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human Histone H2A type 3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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