Name: Human IL-13 Protein (IL1-HM413)
Brand: KactusBio
SKU: IL1-HM413-100UG
Price: 297.0 USD
Availability: InStock

Express System: HEK293
Product Tag: N-His-Avi
Purity: > 90% as determined by Bis-Tris PAGE
Activity: Immobilized Human IL-13, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human IL-13Ra2, hFc Tag with the EC50 of 1.0ug/ml determined by ELISA (QC Test). The affinity constant of 9.47 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gly21-Asn132

Catalog #IL1-HM413

Size

100UG

500UG

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Product Description	Recombinant Human IL-13 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Gly21-Asn132.
Product Background	Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
Product Category	Recombinant Protein / Antibody discovery

Protein	IL-13
Synonyms	IL13; IL-13; interleukin 13; NC30; P600; ALRH; BHR1; MGC116786; MGC116788; MGC116789
Accession	AAK53823
Species	Human
Biotinylated	no
Amino Acid Range	Gly21-Asn132
Molecular Weight	The protein has a predicted MW of 15.3 kDa. Due to glycosylation, the protein migrates to 15 kDa and 25-45 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-13, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human IL-13Ra2, hFc Tag with the EC50 of 1.0ug/ml determined by ELISA (QC Test). The affinity constant of 9.47 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	N-His-Avi
Expression System	HEK293
Purity	> 90% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IL-13Ra1, hFc Tag captured on CM5 Chip via Protein A can bind Human IL-13, His Tag with an affinity constant of 9.47 nM as determined in SPR assay (Biacore T200).
	Immobilized Human IL-13, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human IL-13Ra2, hFc Tag with the EC50 of 1.0ug/ml determined by ELISA (QC Test).
	Human IL-13 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.