Name: Non-biotinylated Human IL-18 R1/CD218a Protein (IL8-HM4R1)
Brand: KactusBio
SKU: IL8-HM4R1-100UG
Price: 148.5 USD
Availability: InStock

Non-biotinylated Human IL-18 R1/CD218a Protein (IL8-HM4R1)

Human IL-18 R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human IL-18, No Tag with an affinity constant of 2.38 nM as determined in SPR assay (Biacore T200).

Human IL-18 R1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human IL-18 R1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 2.38 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Ala19-Arg329

Catalog #IL8-HM4R1

Size

100UG

500UG

Order now, ships by:

[{"id":42618368131294,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"IL8-HM4R1-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Non-biotinylated Human IL-18 R1\/CD218a Protein (IL8-HM4R1) - 100UG","public_title":"100UG","options":["100UG"],"price":14850,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584260178142,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"IL8-HM4R1-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Non-biotinylated Human IL-18 R1\/CD218a Protein (IL8-HM4R1) - 500UG","public_title":"500UG","options":["500UG"],"price":49500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Human IL-18 R1/CD218a Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala19-Arg329.
Product Background	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	IL-18 R1/CD218a
Synonyms	CD218a; IL18Ra; IL18R1; IL1RRP; IL-1 R5; IL-1 Rrp; IL-18 R alpha; IL-18 R1; IL-18Ra
Accession	AAH69575
Species	Human
Biotinylated	no
Amino Acid Range	Ala19-Arg329
Molecular Weight	The protein has a predicted MW of 38.8 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 2.38 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IL-18 R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human IL-18, No Tag with an affinity constant of 2.38 nM as determined in SPR assay (Biacore T200).
	Human IL-18 R1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-18 R1 is greater than 95% as determined by SEC-HPLC.