Name: Human IL-18RAP/IL-18 R beta Protein (IL8-HM2AP)
Brand: KactusBio
SKU: IL8-HM2AP-100UG
Price: 297.0 USD
Availability: InStock

ELISA binding curve of human IL-18RAP hFc tag protein showing mean absorbance versus log biotinylated anti-IL-18RAP antibody concentration

Human IL-18RAP/IL-18 R beta Protein (IL8-HM2AP)

Immobilized Human IL-18RAP, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 27.0ng/ml determined by ELISA.

Human IL-18RAP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human IL-18RAP is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-18RAP, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 27.0ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Phe20-Arg356

Catalog #IL8-HM2AP

Size

100UG

500UG

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Product Description	Recombinant Human IL-18RAP/IL-18 R beta Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe20-Arg356.
Product Background	lactoferrin (LTF), peptidoglycan recognition protein 1 and IL-18 receptor accessory protein (IL18RAP) remained significantly elevated in peripheral monocytes of hypertensive individuals in a separate validation cohort. Interestingly, IL18RAP expression associated with MAP in a cohort of African Americans..
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	IL-18RAP/IL-18 R beta
Synonyms	IL-18 R beta; ACPL; CD218b; CDw218b; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RB; IL18RAP; IL-18R-bet; IL-18R-β; IL-18Rβ
Accession	O95256-1
Species	Human
Biotinylated	no
Amino Acid Range	Phe20-Arg356
Molecular Weight	The protein has a predicted MW of 65.3 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-18RAP, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 27.0ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human IL-18RAP, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 27.0ng/ml determined by ELISA.
	Human IL-18RAP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-18RAP is greater than 95% as determined by SEC-HPLC.

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