Name: Human Jagged 1/JAG1 Protein (JAG-HM101)
Brand: KactusBio
SKU: JAG-HM101-100UG
Price: 330.0 USD
Availability: InStock

Catalog #JAG-HM101

Size

100UG

500UG

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Human Jagged 1/JAG1 Protein (JAG-HM101) Summary

Product Description	Recombinant Human Jagged 1/JAG1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln34-Ser1046.
Product Background	JAGGED1 (JAG1) is composed of a relatively small intracellular domain, a transmembrane domain and a larger extracellular component. JAG1 is widely expressed throughout mammalian development, across many tissues and developmental stages. The Notch signaling pathway and JAG1 in particular have been implicated in multiple forms of cancer and multiple aspects of cancer biology including tumor angiogenesis, neoplastic cell growth, cancer stem cell maintenance and the metastatic process.
Product Category	Recombinant Protein / Cell therapy / Cell culture / Cytokines

Human Jagged 1/JAG1 Protein (JAG-HM101) Specifications/Details

Protein	Jagged 1/JAG1
Synonyms	Jagged1; hJ1; CD339; JAGL1; AGS; AHD; AWS
Accession	P78504-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln34-Ser1046
Molecular Weight	The protein has a predicted MW of 111.56 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.