Human KIR2DL4/CD158d Protein (KIR-HM2L4)
Catalog: KIR-HM2L4
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Product Description | Recombinant Human KIR2DL4/CD158d Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Trp22-His242. |
Product Background |
KIR2DL4 is an unusual killer cell immunoglobulin-like receptor (KIR) family member in terms of its structure, expression, cellular localization, and signaling properties. The most conserved KIR in evolution, it is referred to as a framework KIR gene and is expressed by all natural killer (NK) cells and a subset of T cells. |
Product Category |
Recombinant Protein |
Target |
KIR2DL4/CD158d |
Gene/Protein ID |
Q99706-1 |
Species |
Human |
Exact Sequence |
Trp22-His242 |
Molecular Weight | The protein has a predicted MW of 50.24 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Human HLA-G Free Heavy Chain, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human KIR2DL4, hFc Tag with the EC50 of 43.4ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity | > 90% as determined by Tris-Bis PAGE |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Liquid |
Shipping | Shipped with dry ice. |
Formulation | Supplied as 0.22 um filtered solution in 20mM PB, 500mM NaCl, 200mM L-Arginine (pH 7.4). |
Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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