Human Latent TGF beta 2/TGFB2 Protein (TGF-HM102)
Human Latent TGF beta 2/TGFB2 Protein (TGF-HM102)
  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: The affinity constant of 2.21 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Leu21-Ser414
Catalog #TGF-HM102
Regular price $405.00
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Product Description

Recombinant Human Latent TGF beta 2/TGFB2 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Leu21-Ser414.

Product Background

Transforming growth factor beta(2) (TGF-beta(2)), a growth regulator of human lens epithelial cells (HLECs), also regulates the death of these cells. TGF-beta(2)-induced apoptosis in HLECs was preceded by an induction of reactive oxygen species (ROS) and a decrease in glutathione in the intracellular content, indicating that this factor induces oxidative stress in HLECs.

Product Category

Recombinant Protein / Antibody discovery

Protein

Latent TGF beta 2/TGFB2

Synonyms

TGFB2; TGFBR2; TGFR2; TbetaR-II; TGFβR2; BB105277; TGF-beta 2; TβR-II; TGF-β 2

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Leu21-Ser414

Molecular Weight

The protein has a predicted MW of 46.6 kDa. Due to glycosylation, the protein migrates to 40-60 kDa&12-13 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 2.21 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

N-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human TGF-beta RII, hFc Tag captured on CM5 Chip via Protein A can bind Human Latent TGF beta 2, His Tag with an affinity constant of 2.21 uM as determined in SPR assay (Biacore T200). Human TGF-beta RII, hFc Tag captured on CM5 Chip via Protein A can bind Human Latent TGF beta 2, His Tag with an affinity constant of 2.21 uM as determined in SPR assay (Biacore T200).
Human Latent TGF beta 2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human Latent TGF beta 2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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