Name: Human M-CSF R/CSF1R/CD115 Protein (CSF-HM01R)
Brand: KactusBio
SKU: CSF-HM01R-100UG
Price: 165.0 USD
Availability: InStock

Human M-CSF R/CSF1R/CD115 Protein (CSF-HM01R)

Immobilized Human M-CSF R, No Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-M-CSF R Antibody, hFc Tag with the EC50 of 8.0ng/ml determined by ELISA (QC Test).

Human M-CSF R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Loaded Human M-CSF, His Tag on Anti-His-Biosensor can bind Human M-CSF R, No Tag with an affinity constant of 0.46 µM as determined in BLI assay (Gator® Prime).

The purity of Human M-CSF R is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: No Tag
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human M-CSF R, No Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-M-CSF R Antibody, hFc Tag with the EC50 of 8.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Ile20-Glu512

Catalog #CSF-HM01R

Size

100UG

500UG

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Product Description	Recombinant Human M-CSF R/CSF1R/CD115 Protein is expressed from HEK293 without tag.It contains Ile20-Glu512.
Product Background	CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region.CSF1R is tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	M-CSF R/CSF1R/CD115
Synonyms	CD115; CSF1R; CSF-1-R; CSFR; FMSFIM2; M-CSF R; MCSFR; M-CSFR; C-FMS; FIM2; FMS; HDLS
Accession	P07333-1
Species	Human
Biotinylated	no
Amino Acid Range	Ile20-Glu512
Molecular Weight	The protein has a predicted MW of 54.49 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human M-CSF R, No Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-M-CSF R Antibody, hFc Tag with the EC50 of 8.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	No Tag
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human M-CSF R, No Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-M-CSF R Antibody, hFc Tag with the EC50 of 8.0ng/ml determined by ELISA (QC Test).
	Human M-CSF R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Human M-CSF, His Tag on Anti-His-Biosensor can bind Human M-CSF R, No Tag with an affinity constant of 0.46 µM as determined in BLI assay (Gator® Prime).
	The purity of Human M-CSF R is greater than 95% as determined by SEC-HPLC.

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