Human SIRP Beta/CD172b Protein (SRP-HM40B)
Human SIRP Beta/CD172b Protein (SRP-HM40B)
Human SIRP Beta/CD172b Protein (SRP-HM40B)
Human SIRP Beta/CD172b Protein (SRP-HM40B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Glu30-Ala369
Catalog #SRP-HM40B
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Product Description
 Recombinant Human SIRP Beta/CD172b Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu30-Ala369.
Product Background
 SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like sequence and two C1-set Ig domains.SIRP beta 1 is immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
Product Category
 Recombinant Protein
Target
 SIRP Beta/CD172b
Synonyms
 SIRP-beta-1 isoform 3; SIRPB1; CD172b; DKFZp686A05192; FLJ26614; 9930027N05Rik; SIRP-beta; Sirpb; Sirpb1; Sirpb1a
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Glu30-Ala369
Molecular Weight
 The protein has a predicted MW of 40 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His-Avi
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human SIRP Beta on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
The purity of Human SIRP Beta is greater than 95% as determined by SEC-HPLC.
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