Name: Human SIRP Beta/CD172b Protein (SRP-HM40B)
Brand: KactusBio
SKU: SRP-HM40B-100UG
Price: 297.0 USD
Availability: InStock

Human SIRP Beta/CD172b Protein (SRP-HM40B)

Human SIRP Beta on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

The purity of Human SIRP Beta is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Glu30-Ala369

Catalog #SRP-HM40B

Size

100UG

500UG

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Product Description	Recombinant Human SIRP Beta/CD172b Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu30-Ala369.
Product Background	SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like sequence and two C1-set Ig domains.SIRP beta 1 is immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	SIRP Beta/CD172b
Synonyms	SIRP-beta-1 isoform 3; SIRPB1; CD172b; DKFZp686A05192; FLJ26614; 9930027N05Rik; SIRP-beta; Sirpb; Sirpb1; Sirpb1a;SIRP-β-1 isoform 3; SIRP-β
Accession	O00241-1
Species	Human
Biotinylated	no
Amino Acid Range	Glu30-Ala369
Molecular Weight	The protein has a predicted MW of 40 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human SIRP Beta on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
	The purity of Human SIRP Beta is greater than 95% as determined by SEC-HPLC.